Vaccination for Kidney Patients

VACCINATION FOR KIDNEY PATIENTS

Essential vaccines for people with CKD, dialysis and kidney transplantation

Kidney disease and dialysis can increase the risk of certain infections. Vaccination is an important part of preventive kidney care. The vaccines you need may depend on your age, kidney function, dialysis status and whether you have had a kidney transplant.

Why is vaccination important in kidney disease?

People with chronic kidney disease (CKD), those on dialysis and kidney transplant recipients are at increased risk of infections due to altered immunity. Vaccination helps protect against serious and potentially life-threatening infections. Vaccination should ideally be reviewed and completed before dialysis or kidney transplantation whenever possible.

1. Hepatitis B Vaccine

Engerix-B / Shanvac-B / Enivac B (or any approved brand)

Why important: Hepatitis B infection is a serious risk for patients with advanced CKD, patients approaching dialysis and especially haemodialysis patients. Vaccination is a key part of pre-dialysis care.

Route: Injection into a muscle (upper arm for adults, thigh for infants)

Dose: 2 ml (40 mcg) IM each time

Schedule (confirm with your nephrologist):

  • 1 1st Dose — Day 0
  • 2 2nd Dose — 1st month
  • 3 3rd Dose — 2nd month
  • 4 4th Dose — 6th month

Note: Vaccine response may be lower in advanced CKD. Completing the full series is important.

Anti-HBs Antibody Monitoring

After completing the vaccination series, your nephrologist may check Anti-HBs antibody levels. In dialysis patients, an Anti-HBs level of ≥10 mIU/mL is generally considered protective. Periodic antibody monitoring and booster/revaccination may be required when immunity declines, as advised by your treating nephrologist.

Vaccination should ideally be completed before dialysis or kidney transplantation whenever possible.

2. Influenza Vaccine

Seasonal flu vaccine (Influvac or any approved brand)

Why important: Kidney patients can be at increased risk of complications from influenza. Annual vaccination helps reduce this risk.

Dose: 0.5 ml IM — once every year

When: Take the seasonal influenza vaccine every year at the recommended time for your region. The ideal timing depends on the influenza season and current local recommendations.

3. Pneumococcal Vaccine

Protects against serious pneumococcal infection

Why important: People with CKD, nephrotic syndrome and kidney failure have an increased risk of serious pneumococcal infection.

Important — Your vaccination history matters

The appropriate pneumococcal vaccine and interval depend on your age, CKD stage, dialysis status, immune status and previous pneumococcal vaccination. Currently available options include PCV20, PCV21, PCV15 and PPSV23.

If you have previously received PCV13, PPSV23, PCV15, PCV20 or another pneumococcal vaccine, your next dose may be different. Do not assume that you need another dose without reviewing your vaccination record with your nephrologist.

Ask your nephrologist to review your previous vaccination record before receiving any pneumococcal vaccine.

4. Shingles Vaccine (Shingrix)

Recombinant zoster vaccine — 2 doses

Recommended for:

  • Adults 50 years and older
  • Adults 19 years and older who are immunocompromised or at increased risk, according to current recommendations

Schedule: Usually given as 2 doses. The interval may vary depending on the patient's immune status. Confirm timing with your nephrologist.

Note: Shingrix is a non-live recombinant vaccine. The live shingles vaccine (Zostavax) is generally not recommended for immunocompromised patients.

5. COVID-19 Vaccine

As per current national recommendations

Why important: People with advanced CKD, dialysis patients and transplant recipients may be at increased risk of severe COVID-19.

Keep COVID-19 vaccination up to date according to the current age- and risk-based recommendations in your region.

Kidney transplant patients: Should follow their transplant team's vaccination schedule, as timing may need to be coordinated with immunosuppressive therapy.

6. Tetanus, Diphtheria & Pertussis (Tdap/Td)

Routine adult vaccination

Kidney patients should also remain up to date with routine adult vaccinations, including Tdap/Td according to the applicable adult immunization schedule.

What it protects against: Tetanus (lockjaw), diphtheria and pertussis (whooping cough).

Your nephrologist can advise on the correct booster schedule for your situation.

7. Other Vaccines — Depending on Age and Medical Condition

Your nephrologist may recommend additional vaccines

Your nephrologist may recommend additional vaccines depending on your age, kidney disease, immune status, travel plans and whether you are preparing for kidney transplantation.

These may include:

Hepatitis A
MMR (Measles, Mumps, Rubella)
Varicella
HPV (Human Papillomavirus)
RSV Vaccine
Meningococcal Vaccine
Travel-related vaccines

This list is not exhaustive. Do not assume you need every vaccine listed — your doctor will guide you based on your individual situation.

Kidney Transplant Patients — Important

  • Vaccination planning should ideally be completed before kidney transplantation whenever possible.
  • After transplantation, patients take immunosuppressive medicines which can affect vaccine responses.
  • Do not receive a live vaccine after kidney transplantation unless specifically advised by your transplant team. This includes MMR, Varicella and live shingles vaccines.
  • Vaccination status should be reviewed during transplant evaluation.

Vaccines Before Kidney Transplant

Plan early — some vaccines need time before surgery

Transplant candidates should have their vaccination status reviewed early during the evaluation process because:

  • Some vaccines require multiple doses over several months
  • Live vaccines (e.g., MMR, Varicella) must be given at least 4 weeks before transplantation and after that may be unsafe
  • Vaccine responses may be better before transplantation than after

Your transplant team will guide you on the correct timing. Do not self-schedule vaccinations without transplant team approval.

How to Take Injection (Deltoid Muscle)

Injection into the Deltoid Muscle (Upper Arm)0.5 ml to 1.0 ml for adults | 25-26 gauge needle | 90 degrees angle

Site

Deltoid muscle (upper arm, 2-3 finger widths below shoulder)

Needle

25-26 gauge, 1 inch (25mm) for adults

Angle

90 degrees perpendicular to skin

Important Tips:

  • Use the opposite arm of fistula/AV access (for dialysis patients)
  • Rotate injection sites if giving multiple vaccines
  • 0.5 ml to 1.0 ml volume for adults
  • Inject into the muscle, NOT subcutaneous (under skin)

Emergency Medicines for Vaccination Reactions

Common medicines for mild-to-moderate side effects after vaccination

Reaction (प्रतिक्रिया)Medicine (दवाई)How to Take (कैसे लें)Dose (मात्रा)
Fever (बुखार)Tab Dolo 650 / Crocin 500 mgAfter food (खाने के बाद)1 tab SOS
Body pain / Headache
(शरीर दर्द / सिरदर्द)
Tab Paracetamol 500 mg / CrocinAfter food (खाने के बाद)1 tab SOS
Pain / Swelling at injection site
(टीके की जगह दर्द / सूजन)
Tab Ibuprofen 400 mg / CombiflamAfter food (खाने के बाद)1 tab SOS
Allergic rash / Itching
(एलर्जी की खुजली)
Tab Cetirizine 10 mg / LevocetirizineAfter food (खाने के बाद)1 tab SOS
Vomiting / Nausea
(उल्टी / जी मिचलाना)
Tab Emset 4mg / OndemBefore food (खाने से पहले)1 tab SOS

SOS = जरूरत पड़ने पर (As needed). These medicines are for mild-to-moderate reactions only.

Seek immediate medical attention if you experience:

  • Difficulty breathing or wheezing
  • Swelling of face, lips, tongue or throat
  • Severe dizziness or fainting
  • Rapid heartbeat
  • High fever (>102°F / 39°C) not responding to medicines
  • Severe allergic reaction (anaphylaxis)

Call emergency services or go to the nearest hospital immediately. Do not wait.

Kidney patients: Always check with your nephrologist before taking any medicine, even over-the-counter drugs. Some pain medicines (e.g., NSAIDs like Ibuprofen) may not be suitable for advanced CKD or dialysis patients.

When Should Kidney Patients Discuss Vaccination?

At CKD diagnosis
Before starting dialysis
During dialysis
During transplant evaluation
Before kidney transplantation
After kidney transplantation
Before starting immunosuppressive treatment

Vaccination Record

Use this table to track your vaccines

VaccineDose / DateNext DueRemarks
Hepatitis B___/___/_________/___/____________________
Influenza___/___/_________/___/____________________
Pneumococcal___/___/_________/___/____________________
COVID-19___/___/_________/___/____________________
Shingrix (Shingles)___/___/_________/___/____________________
Tdap / Td___/___/_________/___/____________________
Other: ___________/___/_________/___/____________________

Important Things to Remember

  • Do not wait until dialysis starts to review your vaccination status.
  • Keep a record of all vaccines you have received.
  • Previous vaccination history matters — always share it with your doctor.
  • Vaccine schedules can differ between patients based on age, kidney function and immune status.
  • Kidney transplant patients require special consideration.
  • Some live vaccines may not be appropriate after transplantation.
  • Always tell your doctor about your kidney disease and current medicines before vaccination.

Need help understanding which vaccines you need?

Consult a nephrologist for personalised vaccination advice based on your kidney disease, dialysis status and transplant plans.

Consult a Nephrologist

Medical Disclaimer: This page provides general educational information and does not replace individual medical advice. Vaccination recommendations may vary depending on age, CKD stage, dialysis status, transplant status, immune status, previous vaccination and local guidelines. Please consult your nephrologist or transplant team before receiving vaccines. Vaccination schedules presented here are general guides and may not be appropriate for every patient.